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Home › Research › Topics › statin-lipid-lowering-and-dementia

statin-lipid-lowering-and-dementia

5 studies tagged statin-lipid-lowering-and-dementia, dated 2000-11-01 to 2025-06-27. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Statin Initiation and Dementia Incidence in a Large Health Care System From 1997 to 2020: A Target Trial Emulation Study 2025-06-27
  2. Statin Initiation and Risk of Incident Alzheimer Disease and Cognitive Decline in Genetically Susceptible Older Adults 2024-03-06
  3. Statin use and risk of dementia or Alzheimer's disease: a systematic review and meta-analysis of observational studies 2022-05-01

Studies

5 studies carry this tag.

Date range

2000 to 2025

Top journals

  • Neurology 3
  • European journal of preventive cardiology 1
  • Lancet (London, England) 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Statin Initiation and Dementia Incidence in a Large Health Care System From 1997 to 2020: A Target Trial Emulation Study

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. Neurology 2025-06-27 Prevention and risk

    Among eligible participants (n = 705,061), 264,294 individuals (37.5% of eligible participants) initiated any statin during 2001-2010 ("initiators"), of whom 249,613 (94.4%) were matched with 255,937 unique noninitiators to create the analytic sample (322,358 unique participants; mean age at baseline = 67.4 years; 55.1% female).

  2. Statin Initiation and Risk of Incident Alzheimer Disease and Cognitive Decline in Genetically Susceptible Older Adults

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. Neurology 2024-03-06 Genetics

    Our findings suggest that statins might be associated with a lower risk of incident AD among individuals with the APOE ε4 allele.

  3. Statin use and risk of dementia or Alzheimer's disease: a systematic review and meta-analysis of observational studies

    ✓ Peer-reviewed alzhub usefulness score 64 out of 100. European journal of preventive cardiology 2022-05-01 Prevention and risk

    These results confirm the absence of a neurocognitive risk associated with statin treatment and suggest a potential favourable role of statins.

  4. Randomized controlled trial of atorvastatin in mild to moderate Alzheimer disease: LEADe

    ✓ Peer-reviewed alzhub usefulness score 76 out of 100. Neurology 2010-03-03 Treatments

    In this large-scale randomized controlled trial evaluating statin therapy as a treatment for mild to moderate Alzheimer disease, atorvastatin was not associated with significant clinical benefit over 72 weeks.

  5. Statins and the risk of dementia

    ✓ Peer-reviewed alzhub usefulness score 68 out of 100. Lancet (London, England) 2000-11-01 Getting a diagnosis

    The study encompassed 284 cases with dementia and 1080 controls.

All topic tags with their study counts