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sleep-disruption
2 studies tagged sleep-disruption, dated 2014-01-01 to 2016-01-21. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
Studies
2 studies carry this tag.
Date range
2014 to 2016
Top journals
- Journal of Alzheimer's disease : JAD 1
- Neurobiology of aging 1
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The orexin system has been investigated in patients affected by mild cognitive impairment (MCI) due to Alzheimer's disease (AD) by measuring orexin-A concentrations in the cerebrospinal fluid (CSF), and correlated to subjective and objective sleep parameters, quantified by questionnaires and polysomnography, respectively.
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Circadian misalignment and sleep disruption is evident in patients with MCI, and is consistent with changes observed in Alzheimer's disease.