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sites
3 studies tagged sites, dated 2012-07-11 to 2021-06-21. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Cryptic Sites in Tau Fibrils Explain the Preferential Binding of the AV-1451 PET Tracer toward Alzheimer's Tauopathy 2021-06-21
- Clearance of amyloid-beta in Alzheimer's disease: shifting the action site from center to periphery 2014-04-15
- Predicting sites of new hemorrhage with amyloid imaging in cerebral amyloid angiopathy 2012-07-11
Studies
3 studies carry this tag.
Date range
2012 to 2021
Top journals
- ACS chemical neuroscience 1
- Molecular neurobiology 1
- Neurology 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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In contrast, tau tracer AV-1451 is reported to bind to specific types of tau fibrils (in particular to AD-associated and CTE) with higher binding affinity and only show nonspecific or weaker binding toward tau fibrils dominant with 3R isoforms (associated with PiD).
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36/100
Amyloid-beta (Aβ) is suggested to play a causal role in the pathogenesis of Alzheimer's disease (AD).
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Our results provide direct evidence that new CAA-related hemorrhages occur preferentially at sites of increased amyloid deposition and suggest that PiB-PET imaging may be a useful tool in prediction of incident hemorrhages in patients with CAA.