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Newest in this topic

  1. The GLP-1 agonist semaglutide ameliorates cognitive regression in P301S tauopathy mice model via autophagy/ACE2/SIRT1/FOXO1-Mediated Microglia Polarization 2025-01-26
  2. Potential neuroprotective and autophagy-enhancing effects of alogliptin on lithium/pilocarpine-induced seizures in rats: Targeting the AMPK/SIRT1/Nrf2 axis 2024-07-15
  3. Neuroprotective Impact of Linagliptin against Cadmium-Induced Cognitive Impairment and Neuropathological Aberrations: Targeting SIRT1/Nrf2 Axis, Apoptosis, and Autophagy 2023-07-27

Studies

4 studies carry this tag.

Date range

2017 to 2025

Top journals

  • Current neurovascular research 1
  • European journal of pharmacology 1
  • Life sciences 1
  • Pharmaceuticals (Basel, Switzerland) 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. The GLP-1 agonist semaglutide ameliorates cognitive regression in P301S tauopathy mice model via autophagy/ACE2/SIRT1/FOXO1-Mediated Microglia Polarization

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. European journal of pharmacology 2025-01-26 Drug development

    Tau hyper-phosphorylation has been recognized as an essential contributor to neurodegeneration in Alzheimer's disease (AD) and related tauopathies.

  2. Potential neuroprotective and autophagy-enhancing effects of alogliptin on lithium/pilocarpine-induced seizures in rats: Targeting the AMPK/SIRT1/Nrf2 axis

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Life sciences 2024-07-15 Drug development

    This study suggested that the neuroprotective properties and autophagy-enhancing effects of ALO make it a promising treatment for SE and can potentially be used as a management approach for this condition.

  3. Neuroprotective Impact of Linagliptin against Cadmium-Induced Cognitive Impairment and Neuropathological Aberrations: Targeting SIRT1/Nrf2 Axis, Apoptosis, and Autophagy

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Pharmaceuticals (Basel, Switzerland) 2023-07-27 Drug development

    Cadmium is an environmental contaminant associated with marked neurotoxicity and cognitive impairment.

  4. Moving to the Rhythm with Clock (Circadian) Genes, Autophagy, mTOR, and SIRT1 in Degenerative Disease and Cancer

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Current neurovascular research 2017-01-01 Genetics

    Future targeting of the pathways of autophagy, mTOR, SIRT1, and Wnt that control mammalian circadian rhythm may hold the key for the development of novel and effective therapies against aging- related disorders, neurodegenerative disease, and tumorigenesis.

All topic tags with their study counts