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Home › Research › Topics › simvastatin

simvastatin

7 studies tagged simvastatin, dated 2002-02-01 to 2012-04-01. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Age-dependent rescue by simvastatin of Alzheimer's disease cerebrovascular and memory deficits 2012-04-01
  2. Simvastatin improves cerebrovascular function and counters soluble amyloid-beta, inflammation and oxidative stress in aged APP mice 2009-06-12
  3. Simvastatin enhances learning and memory independent of amyloid load in mice 2006-12-01

Studies

7 studies carry this tag.

Date range

2002 to 2012

Top journals

  • Annals of neurology 1
  • Archives of neurology 1
  • Dementia and geriatric cognitive disorders 1
  • Neurobiology of disease 1
  • Pharmacotherapy 1

7 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Age-dependent rescue by simvastatin of Alzheimer's disease cerebrovascular and memory deficits

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The Journal of neuroscience : the official journal of the Society for Neuroscience 2012-04-01 Drug development

    Alzheimer's disease (AD) is now established as a progressive compromise not only of the neurons but also of the cerebral vasculature.

  2. Simvastatin improves cerebrovascular function and counters soluble amyloid-beta, inflammation and oxidative stress in aged APP mice

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neurobiology of disease 2009-06-12 Drug development

    Cerebrovascular dysfunctions appear to contribute to Alzheimer's disease (AD) pathogenesis and the associated cognitive decline.

  3. Simvastatin enhances learning and memory independent of amyloid load in mice

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Annals of neurology 2006-12-01 Drug development

    Our findings demonstrate that the effects of simvastatin on learning and memory are independent of amyloid beta protein levels.

  4. High doses of simvastatin, pravastatin, and cholesterol reduce brain cholesterol synthesis in guinea pigs

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Steroids 2004-06-01 Drug development

    Recent epidemiological studies suggest that inhibitors of 3-hydroxy-3-methyl-glutaryl CoA reductase, so-called statins, are effective in lowering the prevalence of Alzheimer's disease.

  5. Cognitive impairment associated with atorvastatin and simvastatin

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Pharmacotherapy 2003-12-01 Drug development

    Clinical guidelines for cholesterol testing and management have been updated recently.

  6. Treatment with simvastatin in patients with Alzheimer's disease lowers both alpha- and beta-cleaved amyloid precursor protein

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Dementia and geriatric cognitive disorders 2003-01-01 Drug development

    We investigated the clinical and biological effects of cholesterol-lowering treatment with a statin in 19 patients with Alzheimer's disease.

  7. Reduction of plasma 24S-hydroxycholesterol (cerebrosterol) levels using high-dosage simvastatin in patients with hypercholesterolemia: evidence that simvastatin affects cholesterol metabolism in the human brain

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Archives of neurology 2002-02-01 Drug development

    The greater reduction of plasma concentrations of 24S-hydroxycholesterol compared with cholesterol indicates that simvastatin in a dosage of 80 mg/d reduces cholesterol turnover in the brain.

All topic tags with their study counts