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signal
7 studies tagged signal, dated 2011-02-03 to 2026-10-02. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Safety of lecanemab in real-world patients with Alzheimer's disease: a prospective, observational case series supported by FAERS signal analysis 2026-10-02
- Disproportionality analysis of adverse event signals associated with seven Alzheimer's drugs: insights from the FAERS database 2026-09-24
- Post-marketing safety signals and report-level ARIA-E stratification for lecanemab and donanemab: an integrated FAERS and WHO-VigiAccess pharmacovigilance study 2026-08-18
Studies
7 studies carry this tag.
Date range
2011 to 2026
Top journals
- ACS sensors 1
- American journal of human genetics 1
- Brain : a journal of neurology 1
- Frontiers in neuroinformatics 1
- Frontiers in pharmacology 1
7 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Although clinical trials have demonstrated its favorable safety profile, real-world studies are crucial for identifying rare adverse events (AEs) and evaluating post-marketing safety.
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This study utilized FAERS data to compare adverse event reporting signals for seven anti-AD drugs.
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FAERS included 2961 lecanemab and 1542 donanemab primary suspect reports; WHO-VigiAccess included 2525 lecanemab- and 1450 donanemab-related reports.
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Alzheimer's disease (AD) is a progressive neurodegenerative disorder primarily characterized by cognitive decline and behavioral impairments, typically manifesting in the elderly and presenile population.
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The brain MRI demonstrated new FLAIR hyper signal intensity in subcortical regions of precentral gyri (motor cortex) symmetrically as well as trace subarachnoid hemorrhage at the vertex compatible with ARIA-E and ARIA-H. After tolerating 6 doses of aducanumab a safety MRI revealed new bilateral symmetric FLAIR hyper signal intensity in the subcortical motor cortex.
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Defects of mitochondrial dynamics are emerging causes of neurological disease.
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We have leveraged a Drosophila model relevant to Alzheimer disease (AD) for functional screening of findings from a genome-wide scan for loci associated with a quantitative measure of AD pathology in humans.