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Home › Research › Topics › show

show

6 studies tagged show, dated 2001-08-01 to 2023-12-13. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Longitudinal cerebrospinal fluid measurements show glial hypo- and hyperactivation in predementia Alzheimer's disease 2023-12-13
  2. Human microglia show unique transcriptional changes in Alzheimer's disease 2023-05-29
  3. Immune cells lacking Y chromosome show dysregulation of autosomal gene expression 2021-04-10

Studies

6 studies carry this tag.

Date range

2001 to 2023

Top journals

  • Cellular and molecular life sciences : CMLS 1
  • Experimental neurology 1
  • Journal of neuroinflammation 1
  • Nature aging 1
  • The American journal of pathology 1

6 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Longitudinal cerebrospinal fluid measurements show glial hypo- and hyperactivation in predementia Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. Journal of neuroinflammation 2023-12-13 Biomarkers

    Cross-sectionally, CSF sTREM2, YKL-40, clusterin and fractalkine were higher only in groups with tau pathology, independent of amyloidosis (p < 0.001, A+/T+ or N+ and A-/T+ or N+, compared to A-/T-/N-).

  2. Human microglia show unique transcriptional changes in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Nature aging 2023-05-29 Genetics

    Microglia, the innate immune cells of the brain, influence Alzheimer's disease (AD) progression and are potential therapeutic targets.

  3. Immune cells lacking Y chromosome show dysregulation of autosomal gene expression

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Cellular and molecular life sciences : CMLS 2021-04-10 Genetics

    Epidemiological investigations show that mosaic loss of chromosome Y (LOY) in leukocytes is associated with earlier mortality and morbidity from many diseases in men.

  4. Human DNA methylomes of neurodegenerative diseases show common epigenomic patterns

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Translational psychiatry 2016-01-19 Genetics

    Different neurodegenerative disorders often show similar lesions, such as the presence of amyloid plaques, TAU-neurotangles and synuclein inclusions.

  5. Overexpression of monocyte chemotactic protein-1/CCL2 in beta-amyloid precursor protein transgenic mice show accelerated diffuse beta-amyloid deposition

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The American journal of pathology 2005-05-01 Biomarkers

    Microglia accumulation at the site of amyloid plaques is a strong indication that microglia play a major role in Alzheimer's disease pathogenesis.

  6. Behavioral phenotyping of GFAP-apoE3 and -apoE4 transgenic mice: apoE4 mice show profound working memory impairments in the absence of Alzheimer's-like neuropathology

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Experimental neurology 2001-08-01 Biomarkers

    For the purpose of studying the potential neurobehavioral effects of different human apolipoprotein E (apoE) isoforms produced within the brain, transgenic (TG) mice were generated in which human apoE3 or apoE4 isoforms were under control of an astrocyte-specific, glial fibrillary acidic protein promoter and these TG mice were bred back to apoE knockout (KO) mice.

All topic tags with their study counts