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secretase-cleavage
2 studies tagged secretase-cleavage, dated 2017-08-08 to 2020-08-24. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
Studies
2 studies carry this tag.
Date range
2017 to 2020
Top journals
- The EMBO journal 1
- The Journal of biological chemistry 1
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Sequence variants of the microglial expressed TREM2 (triggering receptor expressed on myeloid cells 2) are a major risk factor for late onset Alzheimer's disease.
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One of the hallmarks of Alzheimer's disease is the formation of extracellular amyloid plaques that consist mainly of abnormally aggregated forms of amyloid β (Aβ) peptides.