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Home › Research › Topics › reduces-tau

reduces-tau

3 studies tagged reduces-tau, dated 2011-03-22 to 2017-03-18. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. MultiTEP platform-based DNA epitope vaccine targeting N-terminus of tau induces strong immune responses and reduces tau pathology in THY-Tau22 mice 2017-03-18
  2. Vectored Intracerebral Immunization with the Anti-Tau Monoclonal Antibody PHF1 Markedly Reduces Tau Pathology in Mutant Tau Transgenic Mice 2016-12-01
  3. Valproate reduces tau phosphorylation via cyclin-dependent kinase 5 and glycogen synthase kinase 3 signaling pathways 2011-03-22

Studies

3 studies carry this tag.

Date range

2011 to 2017

Top journals

  • Brain research bulletin 1
  • The Journal of neuroscience : the official journal of the Society for Neuroscience 1
  • Vaccine 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. MultiTEP platform-based DNA epitope vaccine targeting N-terminus of tau induces strong immune responses and reduces tau pathology in THY-Tau22 mice

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Vaccine 2017-03-18 Drug development

    These data demonstrate that MultiTEP-based DNA epitope vaccination targeting the N-terminus of tau is highly immunogenic and therapeutically potent in the THY-Tau22 mouse model of tauopathy and indicate that EP-mediated DNA immunization is an attractive alternative to protein-based adjuvanted vaccines for inducing high concentrations of anti-tau antibodies.

  2. Vectored Intracerebral Immunization with the Anti-Tau Monoclonal Antibody PHF1 Markedly Reduces Tau Pathology in Mutant Tau Transgenic Mice

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The Journal of neuroscience : the official journal of the Society for Neuroscience 2016-12-01 Drug development

    Passive immunization with anti-tau monoclonal antibodies has been shown by several laboratories to reduce age-dependent tau pathology and neurodegeneration in mutant tau transgenic mice.

  3. Valproate reduces tau phosphorylation via cyclin-dependent kinase 5 and glycogen synthase kinase 3 signaling pathways

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Brain research bulletin 2011-03-22 Drug development

    Valproate (VPA) is a widely used anticonvulsant and mood-stabilizing drug.

All topic tags with their study counts