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reactive-astrocytes
3 studies tagged reactive-astrocytes, dated 2020-11-16 to 2023-08-02. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Human Alzheimer's disease reactive astrocytes exhibit a loss of homeostastic gene expression 2023-08-02
- Reactive Astrocytes Contribute to Alzheimer's Disease-Related Neurotoxicity and Synaptotoxicity in a Neuron-Astrocyte Co-culture Assay 2022-01-21
- Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer's disease via H2O2- production 2020-11-16
Studies
3 studies carry this tag.
Date range
2020 to 2023
Top journals
- Acta neuropathologica communications 1
- Frontiers in cellular neuroscience 1
- Nature neuroscience 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Astrocytes are one of the brain's major cell types and are responsible for maintaining neuronal homeostasis via regulating the extracellular environment, providing metabolic support, and modulating synaptic activity.
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Pathogenesis of presymptomatic disease stages remains elusive, although studies suggest that the early structural and functional alterations likely occur at neuronal dendritic spines.
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Although the pathological contributions of reactive astrocytes have been implicated in Alzheimer's disease (AD), their in vivo functions remain elusive due to the lack of appropriate experimental models and precise molecular mechanisms.