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Newest in this topic

  1. Intracellular Amyloid-β in the Normal Rat Brain and Human Subjects and Its relevance for Alzheimer's Disease 2023-01-01
  2. Oligomers of β-amyloid protein (Aβ1-42) induce the activation of cyclooxygenase-2 in astrocytes via an interaction with interleukin-1β, tumour necrosis factor-α, and a nuclear factor κ-B mechanism in the rat brain 2012-05-14
  3. Amyloid beta-protein (Abeta)1-40 protects neurons from damage induced by Abeta1-42 in culture and in rat brain 2003-11-01

Studies

6 studies carry this tag.

Date range

1988 to 2023

Top journals

  • Brain research bulletin 1
  • Experimental neurology 1
  • Journal of Alzheimer's disease : JAD 1
  • Journal of neurochemistry 1
  • The American journal of pathology 1

6 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Intracellular Amyloid-β in the Normal Rat Brain and Human Subjects and Its relevance for Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Journal of Alzheimer's disease : JAD 2023-01-01 Biomarkers

    Expression of iAβ42 in healthy Wistar rats predominates in the same structures where iAβ accumulates and Aβ plaques initially form in the much used, Wistar based McGill-R-Thy1-APP rat model for AD.

  2. Despite growing evidence indicating the effects of cytokines, including interleukin-1beta (IL-1β) and tumour necrosis factor-α (TNFα), and the enzyme cyclooxygenase-2 (COX-2) in Alzheimer's diseases, little is known about the signalling mechanisms that mediate its activation in response to beta-amyloid protein (Aβ).

  3. Amyloid beta-protein (Abeta)1-40 protects neurons from damage induced by Abeta1-42 in culture and in rat brain

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of neurochemistry 2003-11-01 Biomarkers

    Previously, we found that amyloid beta-protein (Abeta)1-42 exhibits neurotoxicity, while Abeta1-40 serves as an antioxidant molecule by quenching metal ions and inhibiting metal-mediated oxygen radical generation.

  4. Aluminium toxicity in the rat brain: histochemical and immunocytochemical evidence

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Brain research bulletin 2001-05-01 Biomarkers

    Although the neurotoxic actions of aluminium (Al) have been well documented, its contribution to neurodegenerative diseases such as Alzheimer's disease remains controversial.

  5. Phagocytosis and deposition of vascular beta-amyloid in rat brains injected with Alzheimer beta-amyloid

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The American journal of pathology 1992-06-01 Biomarkers

    The presence of extracellular deposits of beta-amyloid protein in the brain is a hallmark of Alzheimer's disease (AD).

  6. Alzheimer's disease amyloidogenic glycoprotein: expression pattern in rat brain suggests a role in cell contact

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The EMBO journal 1988-05-01 Risk genes beyond APOE

    The cloned cDNA encoding the rat cognate of the human A4 amyloid precursor protein was isolated from a rat brain library.

All topic tags with their study counts