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Newest in this topic

  1. Lysosomal proteolysis inhibition selectively disrupts axonal transport of degradative organelles and causes an Alzheimer's-like axonal dystrophy 2011-05-01
  2. Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration 2003-04-18

Studies

2 studies carry this tag.

Date range

2003 to 2011

Top journals

  • Annual review of neuroscience 1
  • The Journal of neuroscience : the official journal of the Society for Neuroscience 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Lysosomal proteolysis inhibition selectively disrupts axonal transport of degradative organelles and causes an Alzheimer's-like axonal dystrophy

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The Journal of neuroscience : the official journal of the Society for Neuroscience 2011-05-01 Risk genes beyond APOE

    In the hallmark neuritic dystrophy of Alzheimer's disease (AD), autophagic vacuoles containing incompletely digested proteins selectively accumulate in focal axonal swellings, reflecting defects in both axonal transport and autophagy.

  2. Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Annual review of neuroscience 2003-04-18 Risk genes beyond APOE

    Intensive studies of three proteins--Presenilin, Notch, and the amyloid precursor protein (APP)--have led to the recognition of a direct intersection between early development and late-life neurodegeneration.

All topic tags with their study counts