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Newest in this topic

  1. L-685,458, an aspartyl protease transition state mimic, is a potent inhibitor of amyloid beta-protein precursor gamma-secretase activity 2000-08-01
  2. The secreted form of the Alzheimer's amyloid precursor protein with the Kunitz domain is protease nexin-II 1989-09-01

Studies

2 studies carry this tag.

Date range

1989 to 2000

Top journals

  • Biochemistry 1
  • Nature 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. L-685,458, an aspartyl protease transition state mimic, is a potent inhibitor of amyloid beta-protein precursor gamma-secretase activity

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Biochemistry 2000-08-01 Risk genes beyond APOE

    Progressive cerebral amyloid beta-protein (A beta) deposition is believed to play a central role in the pathogenesis of Alzheimer's disease (AD).

  2. The secreted form of the Alzheimer's amyloid precursor protein with the Kunitz domain is protease nexin-II

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Nature 1989-09-01 Risk genes beyond APOE

    The A4 protein (or beta-protein) is a 42- or 43-amino-acid peptide present in the extracellular neuritic plaques in Alzheimer's disease and is derived from a membrane-bound amyloid protein precursor (APP).

All topic tags with their study counts