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progressive-aphasia
4 studies tagged progressive-aphasia, dated 2008-01-14 to 2019-01-25. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Genetic screen in a large series of patients with primary progressive aphasia 2019-01-25
- [18F]AV-1451 binding in vivo mirrors the expected distribution of TDP-43 pathology in the semantic variant of primary progressive aphasia 2017-09-14
- Progression of language decline and cortical atrophy in subtypes of primary progressive aphasia 2011-05-01
Studies
4 studies carry this tag.
Date range
2008 to 2019
Top journals
- Alzheimer's & dementia : the journal of the Alzheimer's Association 1
- Dementia and geriatric cognitive disorders 1
- Journal of neurology, neurosurgery, and psychiatry 1
- Neurology 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Our results show that while pathogenic variants within the most common dementia genes were rarely associated with PPA, these were found almost exclusively in GRN and C9orf72, suggesting that PPA is more TDP43- than tau-related in our series.
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[ 18 F]AV-1451 binds in vivo regions that are likely to contain TDP-43 and not significant tau pathology.
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55/100
The results suggest that the unique features, which sharply differentiate the PPA variants at the early to middle stages, may lose their distinctiveness as the degeneration becomes more severe.
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Galantamine is not effective in the behavioral variety of FTD, but a trend of efficacy is shown in the aphasic subgroup, which may be clinically significant.