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Newest in this topic

  1. Relationship between efficacy and preferential targeting of soluble Aβ aggregates 2025-10-01
  2. Relationship Between Therapeutic Activity and Preferential Targeting of Toxic Soluble Aggregates by Amyloid-Beta-Directed Antibodies 2024-04-25

Studies

2 studies carry this tag.

Date range

2024 to 2025

Top journals

  • Alzheimer's & dementia (New York, N. Y.) 1
  • bioRxiv 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Relationship between efficacy and preferential targeting of soluble Aβ aggregates

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Alzheimer's & dementia (New York, N. Y.) 2025-10-01 Treatments

    These results suggest that selectivity for soluble toxic oligomers correlates with clinical efficacy, potentially attenuating monomer competition and amyloid-related imaging abnormalities (ARIA).

  2. Relationship Between Therapeutic Activity and Preferential Targeting of Toxic Soluble Aggregates by Amyloid-Beta-Directed Antibodies

    ⚠ Preprint — not yet peer-reviewed alzhub usefulness score 16 out of 100. bioRxiv 2024-04-25 Treatments

    Overall, these results suggest that selectivity for soluble toxic Aβ oligomers may be a driver of clinical efficacy, with a potentially reduced risk of ARIA if engagement with plaque is minimized.

All topic tags with their study counts