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potency
3 studies tagged potency, dated 2013-09-26 to 2023-02-26. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Site-specific amino acid D-isomerization of Tau R2 and R3 peptides changes the fibril morphology, resulting in attenuation of Tau aggregation inhibitor potency 2023-02-26
- Humanized monoclonal antibody armanezumab specific to N-terminus of pathological tau: characterization and therapeutic potency 2017-05-05
- Structural determinants of Tau aggregation inhibitor potency 2013-09-26
Studies
3 studies carry this tag.
Date range
2013 to 2023
Top journals
- Biochemical and biophysical research communications 1
- Molecular neurodegeneration 1
- The Journal of biological chemistry 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Tau, a microtubule-binding protein, is a major component of neurofibrillary tangles in the brains of Alzheimer's disease patients.
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These findings suggest that Armanezumab could be therapeutic in clinical studies for treatment of AD.
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Small-molecule Tau aggregation inhibitors are under investigation as potential therapeutic agents against Alzheimer disease.