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posterior-cingulate
2 studies tagged posterior-cingulate, dated 2008-07-01 to 2018-10-05. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Involvement of the Precuneus/Posterior Cingulate Cortex Is Significant for the Development of Alzheimer's Disease: A PET (THK5351, PiB) and Resting fMRI Study 2018-10-05
- Abnormal connectivity in the posterior cingulate and hippocampus in early Alzheimer's disease and mild cognitive impairment 2008-07-01
Studies
2 studies carry this tag.
Date range
2008 to 2018
Top journals
- Alzheimer's & dementia : the journal of the Alzheimer's Association 1
- Frontiers in aging neuroscience 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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SSM/PCA identified a significant spatial THK5351 pattern composed by mainly three clusters including precuneus/posterior cingulate cortex (PCC), right and left dorsolateral prefrontal cortex (DLPFC) which accounted for 23.6% of the total subject voxel variance of the data and had 82.6% sensitivity and 79.1% specificity in discriminating AD from healthy controls.
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The fMRI and DTI results confirmed decreased connectivity from both the PCC and hippocampus to the whole brain in MCI and AD and reduction in connectivity between these two regions, which plausibly represents an early imaging biomarker for AD.