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Home › Research › Topics › pigment

pigment

5 studies tagged pigment, dated 2007-06-19 to 2013-12-27. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Relationships between macular pigment optical density and cognitive function in unimpaired and mildly cognitively impaired older adults 2013-12-27
  2. β-Secretase (BACE1) inhibition causes retinal pathology by vascular dysregulation and accumulation of age pigment 2012-08-20
  3. AlphaB-crystallin is found in detergent-resistant membrane microdomains and is secreted via exosomes from human retinal pigment epithelial cells 2010-11-19

Studies

5 studies carry this tag.

Date range

2007 to 2013

Top journals

  • EMBO molecular medicine 1
  • Journal of cellular physiology 1
  • Neurobiology of aging 1
  • Proceedings of the National Academy of Sciences of the United States of America 1
  • The Journal of biological chemistry 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Relationships between macular pigment optical density and cognitive function in unimpaired and mildly cognitively impaired older adults

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neurobiology of aging 2013-12-27 Brain scans and imaging

    Low carotenoid status (especially of the xanthophylls, lutein [L], and zeaxanthin [Z]) is common in older adults and has been associated with a number of degenerative diseases of the central nervous system ranging from retina (e.g., macular degeneration) to brain (e.g., Alzheimer's disease).

  2. β-Secretase (BACE1) inhibition causes retinal pathology by vascular dysregulation and accumulation of age pigment

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. EMBO molecular medicine 2012-08-20 Brain scans and imaging

    β-Secretase (BACE1) is a major drug target for combating Alzheimer's disease (AD).

  3. AlphaB-crystallin is found in detergent-resistant membrane microdomains and is secreted via exosomes from human retinal pigment epithelial cells

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The Journal of biological chemistry 2010-11-19 Brain scans and imaging

    αB-crystallin (αB) is known as an intracellular Golgi membrane-associated small heat shock protein.

  4. Amyloid-beta up-regulates complement factor B in retinal pigment epithelial cells through cytokines released from recruited macrophages/microglia: Another mechanism of complement activation in age-related macular degeneration

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of cellular physiology 2009-07-01 Brain scans and imaging

    One of the earliest signs of age-related macular degeneration (AMD) is the formation of drusen which are extracellular deposits beneath the retinal pigmented epithelium (RPE).

  5. The lipofuscin fluorophore A2E perturbs cholesterol metabolism in retinal pigment epithelial cells

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2007-06-19 Brain scans and imaging

    Proteins involved in cholesterol trafficking are known to contribute to the pathogenesis of atherosclerosis and Alzheimer's disease.

All topic tags with their study counts