pick

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

1. 50/100

   Deep clinical and neuropathological phenotyping of Pick disease

   ✓ Peer-reviewed alzhub usefulness score 50 out of 100. Annals of neurology · 2015-12-25 · Brain scans and imaging

   Pick disease tau neuropathology may originate in limbic/paralimbic cortices.

   • Brain Biology
2. 47/100

   Comparison of extent of tau pathology in patients with frontotemporal dementia with Parkinsonism linked to chromosome 17 (FTDP-17), frontotemporal lobar degeneration with Pick bodies and early onset Alzheimer's disease

   ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Neuropathology and applied neurobiology · 2006-08-01 · Drug development

   In order to gain insight into the pathogenesis of frontotemporal lobar degeneration (FTLD), the mean tau load in frontal cortex was compared in 34 patients with frontotemporal dementia linked to chromosome 17 (FTDP-17) with 12 different mutations in the tau gene (MAPT), 11 patients with sporadic FTLD with Pick bodies and 25 patients with early onset Alzheimer's disease (EOAD).

   • Other Dementias
3. 41/100

   Pick's disease pathology of a missense mutation of S305N of frontotemporal dementia and parkinsonism linked to chromosome 17: another phenotype of S305N

   ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Dementia and geriatric cognitive disorders · 2004-01-01 · Drug development

   We report the second phenotype of frontotemporal dementia and parkinsonism linked to chromosome 17 with S305N similar to Pick's disease pathology in two brothers.

   • Other Dementias
   • Genetics
4. 40/100

   Severity of gliosis in Pick's disease and frontotemporal lobar degeneration: tau-positive glia differentiate these disorders

   ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Brain : a journal of neurology · 2003-04-01 · Biomarkers

   Formalin-fixed brain specimens from sporadic cases with frontotemporal dementia (eight with tau-positive Pick bodies, five with frontotemporal lobar degeneration without inclusions) were compared with those from non-diseased controls (n = 5).

   • Other Dementias
5. 40/100

   Anti-tau phospho-specific Ser262 antibody recognizes a variety of abnormal hyper-phosphorylated tau deposits in tauopathies including Pick bodies and argyrophilic grains

   ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Acta neuropathologica · 2002-08-30 · Drug development

   The rabbit polyclonal anti-tau phospho-specific Ser262 antibody (577814 Calbiochem) recognizes disease-specific band patterns on Western blots of sarkosyl-insoluble fractions in Alzheimer's disease (AD), progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), argyrophilic grain disease (AGD) and Pick's disease (PiD): four bands of 74/72, 68, 64 and 60 kDa in AD, two bands of 68 and 64 kDa in PSP, CBD and AGD, and two bands of 64 and 60 kDa in PiD.

   • Brain Biology
6. 40/100

   A double-labeling immunohistochemical study of tau exon 10 in Alzheimer's disease, progressive supranuclear palsy and Pick's disease

   ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Acta neuropathologica · 2000-09-01 · Drug development

   Neurofibrillary tangles (NFT), one of the histopathological hallmarks of Alzheimer's disease (AD) and progressive supranuclear palsy (PSP), and Pick bodies in Pick's disease (PiD) are composed of microtubule-associated protein tau, which is the product of alternative splicing of a gene on chromosome 17.

   • Treatments

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