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phosphatidylinositol
2 studies tagged phosphatidylinositol, dated 2006-06-08 to 2010-11-03. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Phosphatidylinositol 3-kinase (PI3K) signaling via glycogen synthase kinase-3 (Gsk-3) regulates DNA methylation of imprinted loci 2010-11-03
- Acetylcholinesterase inhibitors used in treatment of Alzheimer's disease prevent glutamate neurotoxicity via nicotinic acetylcholine receptors and phosphatidylinositol 3-kinase cascade 2006-06-08
Studies
2 studies carry this tag.
Date range
2006 to 2010
Top journals
- Neuropharmacology 1
- The Journal of biological chemistry 1
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Glycogen synthase kinase-3 (Gsk-3) isoforms, Gsk-3α and Gsk-3β, are constitutively active, largely inhibitory kinases involved in signal transduction.
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We show here that donepezil, galanathamine and tacrine, therapeutic acetylcholinesterase inhibitors currently being used for treatment of Alzheimer's disease, protect neuronal cells in a time- and concentration-dependent manner from glutamate neurotoxicity that involves apoptosis.