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Newest in this topic

  1. Longitudinal Phospho-tau217 Predicts Amyloid Positron Emission Tomography in Asymptomatic Alzheimer's Disease 2024-01-01
  2. Head-to-head comparison of plasma and PET imaging ATN markers in subjects with cognitive complaints 2023-06-29
  3. Population pharmacokinetic-pharmacodynamic analyses of amyloid positron emission tomography and plasma biomarkers for lecanemab in subjects with early Alzheimer's disease 2022-09-27

Studies

4 studies carry this tag.

Date range

2010 to 2024

Top journals

  • Brain : a journal of neurology 1
  • CPT: pharmacometrics & systems pharmacology 1
  • The journal of prevention of Alzheimer's disease 1
  • Translational neurodegeneration 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Longitudinal Phospho-tau217 Predicts Amyloid Positron Emission Tomography in Asymptomatic Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. The journal of prevention of Alzheimer's disease 2024-01-01 Biomarkers

    An ECL immunoassay testing plasma P-tau217 accurately predicts amyloid PET positivity in cognitively unimpaired individuals.

  2. Head-to-head comparison of plasma and PET imaging ATN markers in subjects with cognitive complaints

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Translational neurodegeneration 2023-06-29 Biomarkers

    Plasma p-tau181, as well as 18 F-florbetapir and 18 F-Florzolotau PET imaging can be considered as interchangeable biomarkers in the assessment of Aβ status in symptomatic stages of AD. 18 F-Florzolotau and 18 F-FDG PET imaging could serve as biomarkers for the severity of cognitive impairment.

  3. Population pharmacokinetic-pharmacodynamic analyses of amyloid positron emission tomography and plasma biomarkers for lecanemab in subjects with early Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. CPT: pharmacometrics & systems pharmacology 2022-09-27 Biomarkers

    Lecanemab is a humanized immunoglobulin G1 monoclonal antibody that selectively binds to soluble Aβ aggregate species, while demonstrating low affinity for Aβ monomer.

  4. In summary, high (11)C-Pittsburgh Compound B positron emission tomography retention significantly correlates with both fibrillar β-amyloid and losses of neuronal nicotinic acetylcholine receptor subtypes at autopsy, suggesting a closer involvement of β-amyloid pathology with neuronal nicotinic acetylcholine receptor subtypes than with inflammatory processes.

All topic tags with their study counts