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oxidation
4 studies tagged oxidation, dated 2005-01-01 to 2010-06-21. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Cholesterol oxidation in the retina: implications of 7KCh formation in chronic inflammation and age-related macular degeneration 2010-06-21
- Role of by-products of lipid oxidation in Alzheimer's disease brain: a focus on acrolein 2010-01-01
- Cholesterol oxidation products and disease: an emerging topic of interest in medicinal chemistry 2009-01-01
Studies
4 studies carry this tag.
Date range
2005 to 2010
Top journals
- Current medicinal chemistry 1
- Journal of Alzheimer's disease : JAD 1
- Journal of lipid research 1
- Journal of neurochemistry 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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This review will discuss the formation and potential implications of 7-ketocholesterol (7KCh) in the retina. 7KCh is a proinflammatory oxysterol known to be present in high amounts in oxidized LDL deposits associated with atheromatous plaques. 7KCh is generated in situ in these lipoprotein deposits where it can accumulate and reach very high concentrations.
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Abundant data consistently support the idea that oxidative stress occurs and is a constant feature of Alzheimer's disease (AD).
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36/100
Oxysterols are a family of 27-carbon cholesterol oxidation derivatives that may be absorbed with the diet or originated endogenously.
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Increased damage to proteins by glycation, oxidation and nitration has been implicated in neuronal cell death leading to Alzheimer's disease (AD).