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Home › Research › Topics › overexpression

overexpression

4 studies tagged overexpression, dated 2005-05-01 to 2013-04-21. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Overexpression of Hsp27 ameliorates symptoms of Alzheimer's disease in APP/PS1 mice 2013-04-21
  2. Peripheral administration of antisense oligonucleotides targeting the amyloid-β protein precursor reverses AβPP and LRP-1 overexpression in the aged SAMP8 mouse brain 2012-01-01
  3. Axonal transport rates in vivo are unaffected by tau deletion or overexpression in mice 2008-02-01

Studies

4 studies carry this tag.

Date range

2005 to 2013

Top journals

  • Cell stress & chaperones 1
  • Journal of Alzheimer's disease : JAD 1
  • The American journal of pathology 1
  • The Journal of neuroscience : the official journal of the Society for Neuroscience 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Overexpression of Hsp27 ameliorates symptoms of Alzheimer's disease in APP/PS1 mice

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Cell stress & chaperones 2013-04-21 Treatments

    Hsp27 belongs to the small heat shock protein family, which are ATP-independent chaperones.

  2. Peripheral administration of antisense oligonucleotides targeting the amyloid-β protein precursor reverses AβPP and LRP-1 overexpression in the aged SAMP8 mouse brain

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Journal of Alzheimer's disease : JAD 2012-01-01 Drug development

    The senescence accelerated mouse-prone 8 (SAMP8) mouse model of Alzheimer's disease has a natural mutation leading to age-related increases in the amyloid-β protein precursor (AβPP) and amyloid-β (Aβ) in the brain, memory impairment, and deficits in Aβ removal from the brain.

  3. Axonal transport rates in vivo are unaffected by tau deletion or overexpression in mice

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The Journal of neuroscience : the official journal of the Society for Neuroscience 2008-02-01 Biomarkers

    Elevated tau expression has been proposed as a possible basis for impaired axonal transport in Alzheimer's disease.

  4. Overexpression of monocyte chemotactic protein-1/CCL2 in beta-amyloid precursor protein transgenic mice show accelerated diffuse beta-amyloid deposition

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The American journal of pathology 2005-05-01 Biomarkers

    Microglia accumulation at the site of amyloid plaques is a strong indication that microglia play a major role in Alzheimer's disease pathogenesis.

All topic tags with their study counts