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origin
5 studies tagged origin, dated 1994-02-01 to 2019-08-06. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Tau-Reactive Endogenous Antibodies: Origin, Functionality, and Implications for the Pathophysiology of Alzheimer's Disease 2019-08-06
- On the origin of proteins in human drusen: The meet, greet and stick hypothesis 2018-12-17
- DNA hypomethylation in the origin and pathogenesis of human diseases 2009-03-27
Studies
5 studies carry this tag.
Date range
1994 to 2019
Top journals
- Cellular and molecular life sciences : CMLS 1
- Journal of immunology research 1
- Neuropathology and applied neurobiology 1
- Progress in retinal and eye research 1
- The Journal of neuroscience : the official journal of the Society for Neuroscience 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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In Alzheimer's disease (AD), tau pathology manifested by the accumulation of intraneuronal tangles and soluble toxic oligomers emerges as a promising therapeutic target.
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Retinal drusen formation is not only a clinical hallmark for the development of age-related macular degeneration (AMD) but also for other disorders, such as Alzheimer's disease and renal diseases.
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The pathogenesis of any given human disease is a complex multifactorial process characterized by many biologically significant and interdependent alterations.
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The sporadic nature of Alzheimer's disease (AD) argues for an environmental link that may drive AD pathogenesis; however, the triggering factors and the period of their action are unknown.
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Studies employing a bank of antisera applied to sections of LR White embedded AD and normal ageing brain tissue, may throw new light on the derivation of CA. Conspicuous levels of immunoreactivity were found in the CA of both tissues with markers for oligodendrocytic proteins such as antisera against myelin basic proteolipid protein, galactocerebroside and myelin/oligodendrocyte glycoprotein.