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Home › Research › Topics › orally

orally

3 studies tagged orally, dated 2011-11-01 to 2020-03-20. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Safety and pharmacokinetics of the orally available antiprionic compound PRI-002: A single and multiple ascending dose phase I study 2020-03-20
  2. 1,4-Oxazine β-Secretase 1 (BACE1) Inhibitors: From Hit Generation to Orally Bioavailable Brain Penetrant Leads 2015-10-10
  3. Robust central reduction of amyloid-β in humans with an orally available, non-peptidic β-secretase inhibitor 2011-11-01

Studies

3 studies carry this tag.

Date range

2011 to 2020

Top journals

  • Alzheimer's & dementia (New York, N. Y.) 1
  • Journal of medicinal chemistry 1
  • The Journal of neuroscience : the official journal of the Society for Neuroscience 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Safety and pharmacokinetics of the orally available antiprionic compound PRI-002: A single and multiple ascending dose phase I study

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Alzheimer's & dementia (New York, N. Y.) 2020-03-20 Treatments

    The safety and PK results encourage further clinical development of PRI-002.

  2. 1,4-Oxazine β-Secretase 1 (BACE1) Inhibitors: From Hit Generation to Orally Bioavailable Brain Penetrant Leads

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of medicinal chemistry 2015-10-10 Treatments

    1,4-Oxazines are presented, which show good in vitro inhibition in enzymatic and cellular BACE1 assays.

  3. Robust central reduction of amyloid-β in humans with an orally available, non-peptidic β-secretase inhibitor

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. The Journal of neuroscience : the official journal of the Society for Neuroscience 2011-11-01 Risk genes beyond APOE

    According to the amyloid cascade hypothesis, cerebral deposition of amyloid-β peptide (Aβ) is critical for Alzheimer's disease (AD) pathogenesis.

All topic tags with their study counts