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neurotoxic
3 studies tagged neurotoxic, dated 2010-05-27 to 2019-06-15. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Neurotoxic astrocytes express the d-serine synthesizing enzyme, serine racemase, in Alzheimer's disease 2019-06-15
- Stabilization of neurotoxic Alzheimer amyloid-beta oligomers by protein engineering 2010-08-16
- The basal forebrain cholinergic system in aging and dementia. Rescuing cholinergic neurons from neurotoxic amyloid-β42 with memantine 2010-05-27
Studies
3 studies carry this tag.
Date range
2010 to 2019
Top journals
- Behavioural brain research 1
- Neurobiology of disease 1
- Proceedings of the National Academy of Sciences of the United States of America 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Although β-amyloid plaques are a well-recognized hallmark of Alzheimer's disease (AD) neuropathology, no drugs reducing amyloid burden have shown efficacy in clinical trials, suggesting that once AD symptoms emerge, disease progression becomes independent of Aβ production.
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Soluble oligomeric aggregates of the amyloid-beta peptide (Abeta) have been implicated in the pathogenesis of Alzheimer's disease (AD).
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The dysfunction and loss of basal forebrain cholinergic neurons and their cortical projections are among the earliest pathological events in the pathogenesis of Alzheimer's disease (AD).