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Newest in this topic

  1. Neurotoxic astrocytes express the d-serine synthesizing enzyme, serine racemase, in Alzheimer's disease 2019-06-15
  2. Stabilization of neurotoxic Alzheimer amyloid-beta oligomers by protein engineering 2010-08-16
  3. The basal forebrain cholinergic system in aging and dementia. Rescuing cholinergic neurons from neurotoxic amyloid-β42 with memantine 2010-05-27

Studies

3 studies carry this tag.

Date range

2010 to 2019

Top journals

  • Behavioural brain research 1
  • Neurobiology of disease 1
  • Proceedings of the National Academy of Sciences of the United States of America 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Neurotoxic astrocytes express the d-serine synthesizing enzyme, serine racemase, in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Neurobiology of disease 2019-06-15 Treatments

    Although β-amyloid plaques are a well-recognized hallmark of Alzheimer's disease (AD) neuropathology, no drugs reducing amyloid burden have shown efficacy in clinical trials, suggesting that once AD symptoms emerge, disease progression becomes independent of Aβ production.

  2. Stabilization of neurotoxic Alzheimer amyloid-beta oligomers by protein engineering

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2010-08-16 Risk genes beyond APOE

    Soluble oligomeric aggregates of the amyloid-beta peptide (Abeta) have been implicated in the pathogenesis of Alzheimer's disease (AD).

  3. The basal forebrain cholinergic system in aging and dementia. Rescuing cholinergic neurons from neurotoxic amyloid-β42 with memantine

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Behavioural brain research 2010-05-27 Treatments

    The dysfunction and loss of basal forebrain cholinergic neurons and their cortical projections are among the earliest pathological events in the pathogenesis of Alzheimer's disease (AD).

All topic tags with their study counts