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Home › Research › Topics › n-terminal

n-terminal

4 studies tagged n-terminal, dated 2004-10-01 to 2024-02-17. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Plasma N-terminal containing tau fragments (NTA-tau): a biomarker of tau deposition in Alzheimer's Disease 2024-02-17
  2. N-terminal and mid-region tau fragments as fluid biomarkers in neurological diseases 2022-08-01
  3. Role of the Tau N-terminal region in microtubule stabilization revealed by new endogenous truncated forms 2015-05-14

Studies

4 studies carry this tag.

Date range

2004 to 2024

Top journals

  • Brain : a journal of neurology 1
  • Molecular neurodegeneration 1
  • Scientific reports 1
  • The American journal of pathology 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Plasma N-terminal containing tau fragments (NTA-tau): a biomarker of tau deposition in Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 74 out of 100. Molecular neurodegeneration 2024-02-17 Biomarkers

    However, because these biomarkers are strongly associated with the emergence of Aβ pathology, it is difficult to determine the contribution of insoluble tau aggregates to the plasma p-tau signal in blood.

  2. N-terminal and mid-region tau fragments as fluid biomarkers in neurological diseases

    ✓ Peer-reviewed alzhub usefulness score 59 out of 100. Brain : a journal of neurology 2022-08-01 Biomarkers

    After analytical validation, the diagnostic performance of these biomarkers was evaluated in CSF and compared with the Innotest total tau (and as proof of concept, with N-p-tau181 and N-p-tau217) in three clinical cohorts (n = 342 total).

  3. Role of the Tau N-terminal region in microtubule stabilization revealed by new endogenous truncated forms

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Scientific reports 2015-05-14 Genetics

    Tau is a central player in Alzheimer's disease (AD) and related Tauopathies, where it is found as aggregates in degenerating neurons.

  4. Massive CA1/2 neuronal loss with intraneuronal and N-terminal truncated Abeta42 accumulation in a novel Alzheimer transgenic model

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The American journal of pathology 2004-10-01 Risk genes beyond APOE

    Alzheimer's disease (AD) is characterized by a substantial degeneration of pyramidal neurons and the appearance of neuritic plaques and neurofibrillary tangles.

All topic tags with their study counts