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n-methyl-d-aspartate-receptor
3 studies tagged n-methyl-d-aspartate-receptor, dated 1997-01-01 to 2004-11-02. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Memantine blocks alpha7* nicotinic acetylcholine receptors more potently than n-methyl-D-aspartate receptors in rat hippocampal neurons 2004-11-02
- Decreased expression of N-methyl-D-aspartate receptor 1 messenger RNA in select regions of Alzheimer brain 1997-08-01
- Psychotogenicity and N-methyl-D-aspartate receptor antagonism: implications for neuroprotective pharmacotherapy 1997-01-01
Studies
3 studies carry this tag.
Date range
1997 to 2004
Top journals
- Biological psychiatry 1
- Neuroscience 1
- The Journal of pharmacology and experimental therapeutics 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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The N-methyl-d-aspartate (NMDA) receptor antagonist memantine is an approved drug for treatment of Alzheimer's disease (AD).
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An antisense oligonucleotide probe was used to examine the expression of gene encoding the obligatory NMDAR1 subunit of the N-methyl-D-aspartate receptor in the hippocampus and adjacent cortical areas (entorhinal and perirhinal cortices) of seven Alzheimer patients and in the same brain regions of seven control individuals.
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The development of neuroprotective agents for the prevention of neuronal loss in acute conditions such as stroke and epilepsy or chronic neurodegenerative disorders including Parkinson's disease, Alzheimer's disease, Huntington's chorea, and motor neuron disease is currently focusing on drugs that inhibit excitatory amino acid neurotransmission or exhibit antioxidant properties.