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Newest in this topic

  1. Cholinergic treatments with emphasis on m1 muscarinic agonists as potential disease-modifying agents for Alzheimer's disease 2008-07-01
  2. Treatment with the selective muscarinic m1 agonist talsaclidine decreases cerebrospinal fluid levels of A beta 42 in patients with Alzheimer's disease 2003-03-01
  3. M1 muscarinic agonists can modulate some of the hallmarks in Alzheimer's disease: implications in future therapy 2003-01-01

Studies

4 studies carry this tag.

Date range

2000 to 2008

Top journals

  • Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 1
  • Annals of neurology 1
  • Journal of molecular neuroscience : MN 1
  • Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Cholinergic treatments with emphasis on m1 muscarinic agonists as potential disease-modifying agents for Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 2008-07-01 Treatments

    The only prescribed drugs for treatment of Alzheimer's disease (AD) are acetylcholinesterase inhibitors (e.g., donepezil, rivastigmine, galantamine, and tacrine) and memantine, an NMDA antagonist.

  2. Treatment with the selective muscarinic m1 agonist talsaclidine decreases cerebrospinal fluid levels of A beta 42 in patients with Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 72 out of 100. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2003-03-01 Treatments

    The amyloid beta-peptides A beta 40 and A beta 42 are highly amyloidogenic constituents of brain beta-amyloid plaques in Alzheimer's disease (AD).

  3. M1 muscarinic agonists can modulate some of the hallmarks in Alzheimer's disease: implications in future therapy

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of molecular neuroscience : MN 2003-01-01 Treatments

    M1 muscarinic receptors (M1 mAChRs) play a role in an apparent linkage of three major hallmarks of Alzheimer's disease (AD): beta-amyloid (Abeta) peptide; tau hyperphosphorylation and paired helical filaments (PHFs); and loss of cholinergic function conducive to cognitive impairments.

  4. The selective muscarinic M1 agonist AF102B decreases levels of total Abeta in cerebrospinal fluid of patients with Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 47 out of 100. Annals of neurology 2000-12-01 Treatments

    beta-Amyloid (Abeta) deposits in diffuse and compact senile plaques in the brain are one of the defining histopathological features of Alzheimer's disease (AD).

All topic tags with their study counts