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monoamine-oxidase
3 studies tagged monoamine-oxidase, dated 1990-01-01 to 2019-03-27. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Cross-interaction of tau PET tracers with monoamine oxidase B: evidence from in silico modelling and in vivo imaging 2019-03-27
- Design, synthesis, pharmacological evaluation, QSAR analysis, molecular modeling and ADMET of novel donepezil-indolyl hybrids as multipotent cholinesterase/monoamine oxidase inhibitors for the potential treatment of Alzheimer's disease 2014-01-27
- Expression of monoamine oxidase B activity in astrocytes of senile plaques 1990-01-01
Studies
3 studies carry this tag.
Date range
1990 to 2019
Top journals
- Acta neuropathologica 1
- European journal of medicinal chemistry 1
- European journal of nuclear medicine and molecular imaging 1
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The developed tau tracers show in silico and in vivo evidence of cross-interaction with MAO-B; the MAO-B component of the tracer binding was dependent on the regional concentration of the enzyme.
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The design, synthesis, and pharmacological evaluation of donepezil-indolyl based amines 7-10, amides 12-16, and carboxylic acid derivatives 5 and 11, as multipotent ASS234 analogs, able to inhibit simultaneously cholinesterase (ChE) and monoamine oxidase (MAO) enzymes for the potential treatment of Alzheimer's disease (AD), is reported.
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Monoamine oxidase (MAO) histochemistry has been performed in brains from patients with dementia of Alzheimer type (DAT) and aged controls.