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monkey
3 studies tagged monkey, dated 2008-01-01 to 2022-06-24. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Effect of the ABCA1 agonist CS-6253 on amyloid-β and lipoprotein metabolism in cynomolgus monkeys 2022-06-24
- Neurodegenerative disease biomarkers Aβ1-40, Aβ1-42, tau, and p-tau181 in the vervet monkey cerebrospinal fluid: Relation to normal aging, genetic influences, and cerebral amyloid angiopathy 2018-01-13
- Alzheimer's disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (Pb): evidence for a developmental origin and environmental link for AD 2008-01-01
Studies
3 studies carry this tag.
Date range
2008 to 2022
Top journals
- Alzheimer's research & therapy 1
- Brain and behavior 1
- The Journal of neuroscience : the official journal of the Society for Neuroscience 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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43/100
Treatment with the ABCA1 agonist CS-6253 appears to favor Aβ clearance from the brain.
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Overall, these results support the vervet as a non-human primate model of amyloid-related neurodegeneration, such as Alzheimer's disease and cerebral amyloid angiopathy, and highlight Aβ 1-40 and p-tau 181 as potentially valuable biomarkers of these processes.
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The sporadic nature of Alzheimer's disease (AD) argues for an environmental link that may drive AD pathogenesis; however, the triggering factors and the period of their action are unknown.