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molecular-mechanisms
6 studies tagged molecular-mechanisms, dated 2006-02-10 to 2025-03-26. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Molecular mechanisms and biomarkers in neurodegenerative disorders: a comprehensive review 2025-03-26
- Molecular mechanisms of signaling via the docosanoid neuroprotectin D1 for cellular homeostasis and neuroprotection 2017-06-14
- Screening of biochemical and molecular mechanisms of secondary injury and repair in the brain after experimental blast-induced traumatic brain injury in rats 2013-06-05
Studies
6 studies carry this tag.
Date range
2006 to 2025
Top journals
- Chemical research in toxicology 1
- International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1
- Journal of neurotrauma 1
- Molecular biology reports 1
- Neurobiology of disease 1
6 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Neurodegenerative disorders, including Alzheimer's disease (AD), Parkinson's disease (PD), Amyotrophic Lateral Sclerosis (ALS), and Huntington's disease (HD), are significant global health challenges, owing to their profound impact on cognitive, motor, and behavioral functions.
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Docosahexaenoic acid, enriched in the brain and retina, generates docosanoids in response to disruptions of cellular homeostasis.
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Ascorbate, LMWT, and protein thiols were reduced at 2 and 24 h; by 24 h, HNE was increased.
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Combined preventive and therapeutic physical/cognitive stimulation starting before disease onset and continuing over its progression reduce Alzheimer-related pathology in transgenic mice.
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Acrolein and 4-hydroxy-2-nonenal (HNE) are byproducts of lipid peroxidation and are thought to play central roles in various traumatic injuries and disease states that involve cellular oxidative stress, for example, spinal cord trauma, diabetes, and Alzheimer's disease.
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There is compelling evidence that Alzheimer's disease (AD) amyloid-beta (Abeta) deposition is associated with a local inflammatory response, which is initiated by the activation of microglia and the recruitment of astrocytes.