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modifies
2 studies tagged modifies, dated 2015-09-01 to 2021-11-01. Bibliography: BibTeX (.bib) · RIS (.ris)
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Studies
2 studies carry this tag.
Date range
2015 to 2021
Top journals
- Brain : a journal of neurology 1
- Molecular psychiatry 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Recent studies in cognitively unimpaired elderly individuals suggest that the APOE ε4 allele exerts a dosage-dependent effect on brain tau deposition.
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We have sequenced the complete genomes of 72 individuals affected with early-onset familial Alzheimer's disease caused by an autosomal dominant, highly penetrant mutation in the presenilin-1 (PSEN1) gene, and performed genome-wide association testing to identify variants that modify age at onset (AAO) of Alzheimer's disease.