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Home › Research › Topics › microglial-activation

microglial-activation

5 studies tagged microglial-activation, dated 2013-01-30 to 2023-11-20. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. TFEB-vacuolar ATPase signaling regulates lysosomal function and microglial activation in tauopathy 2023-11-20
  2. Individual regional associations between Aβ-, tau- and neurodegeneration (ATN) with microglial activation in patients with primary and secondary tauopathies 2023-07-26
  3. Microglial Activation, Tau Pathology, and Neurodegeneration Biomarkers Predict Longitudinal Cognitive Decline in Alzheimer's Disease Continuum 2022-06-30

Studies

5 studies carry this tag.

Date range

2013 to 2023

Top journals

  • Frontiers in aging neuroscience 1
  • Journal of immunology (Baltimore, Md. : 1950) 1
  • Molecular neurodegeneration 1
  • Molecular psychiatry 1
  • Nature neuroscience 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. TFEB-vacuolar ATPase signaling regulates lysosomal function and microglial activation in tauopathy

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Nature neuroscience 2023-11-20 Genetics

    Transcription factor EB (TFEB) mediates gene expression through binding to the coordinated lysosome expression and regulation (CLEAR) sequence.

  2. Individual regional associations between Aβ-, tau- and neurodegeneration (ATN) with microglial activation in patients with primary and secondary tauopathies

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Molecular psychiatry 2023-07-26 TREM2 and immune genetics

    β-amyloid (Aβ) and tau aggregation as well as neuronal injury and atrophy (ATN) are the major hallmarks of Alzheimer's disease (AD), and biomarkers for these hallmarks have been linked to neuroinflammation.

  3. Microglial Activation, Tau Pathology, and Neurodegeneration Biomarkers Predict Longitudinal Cognitive Decline in Alzheimer's Disease Continuum

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. Frontiers in aging neuroscience 2022-06-30 Biomarkers

    Baseline CSF Aβ42/Aβ40 ratio was decreased in MCI and AD compared to CN, while CSF p-tau181 and t-tau increased.

  4. Temporal gene profiling of the 5XFAD transgenic mouse model highlights the importance of microglial activation in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Molecular neurodegeneration 2014-09-11 Genetics

    Overall, our data suggest that, from M4 to M9, sustained microglial activation becomes the predominant feature and point out that both detrimental and neuroprotective mechanisms appear to be at play in this model.

  5. IFN-γ Production by amyloid β-specific Th1 cells promotes microglial activation and increases plaque burden in a mouse model of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of immunology (Baltimore, Md. : 1950) 2013-01-30 Risk genes beyond APOE

    Alzheimer's disease (AD) is characterized by the presence of amyloid-β (Aβ)-containing plaques, neurofibrillary tangles, and neuronal loss in the brain.

All topic tags with their study counts