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microbiota-gut-brain
100 studies tagged microbiota-gut-brain, dated 1995-01-01 to 2026-10-08. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- The Gut–Liver–Brain Axis in Neurodegeneration: Unraveling Metabolic–Immune Crosstalk from Peripheral Sensing to Central Vulnerability 2026-10-08
- The microbiota-gut-brain axis in mental and neurodegenerative disorders: opportunities for prevention and intervention 2025-10-01
- Microbiota-gut-brain axis in neurodegenerative diseases: molecular mechanisms and therapeutic targets 2025-09-15
Studies
100 studies carry this tag.
Date range
1995 to 2026
Top journals
- Journal of neuroinflammation 4
- Frontiers in cellular and infection microbiology 3
- Frontiers in immunology 3
- Nutrients 3
- AIMS microbiology 2
86 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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41/100
The human microbiota has a fundamental role in host physiology and pathology.
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41/100
Gut microbiota represents a complex physiological ecosystem that influences the host health.
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The purpose of this article is to highlight how sex differences in the gut-brain axis may contribute to the discrepancies in incidence of neurodevelopmental, psychiatric, and neurodegenerative disorders between females and males.
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These data for the first time provide evidence of potential causal links between gut microbiome and AD, MDD, and SCZ.
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The intestinal barrier is essential in human health and constitutes the interface between the outside and the internal milieu of the body.
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The gut microbiome is increasingly implicated in modifying susceptibility to and progression of neurodegenerative diseases (NDs).
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69/100
This population-based cohort study demonstrates significant association between IBD and subsequent development of dementia.
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Opioid drugs are widely used to treat chronic pain, but their misuse can lead to tolerance, dependence, and addiction and have created a significant public health problem.
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Growing evidence highlights the relevance of microbiota-gut-brain axis in the maintenance of brain homeostasis as well as in the pathophysiology of major neurological and psychiatric disorders, including Parkinson's disease (PD), Alzheimer's disease (AD), multiple sclerosis (MS), autism spectrum disorder (ASD) and major depressive disorder (MDD).
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Mucus is integral to gut health and its properties may be affected in neurological disease.
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Of 541 identified studies, 34 were included in the analysis.
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There is increasing evidence showing that the dynamic changes in the gut microbiota can alter brain physiology and behavior.
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Recent data suggest gut microbiota dysbiosis as a contributing factor in neurodegenerative diseases, such as Parkinson's Disease (PD) and Alzheimer's Disease (AD), and these pathologies may manifest via the microbiota-gut-brain-axis, which comprises bidirectional communication through neuroimmune, neuroendocrine, and direct neural pathways such as the vagus nerve.
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In the first part, we introduce the GBA and its relevance, followed by the changes occurring in the GBA during neurodegenerative disorders and then further discuss its role in the pathogenesis of these diseases.
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The gut microbiome - the largest reservoir of microorganisms of the human body - is emerging as an important player in neurodevelopment and ageing as well as in brain diseases including stroke, Alzheimer's disease and Parkinson's disease.
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The gut microbiome was extensively researched for its biological variety and its potential role in propagating diseases outside of the gastrointestinal (GI) tract.
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Research into the role of the gut microbiome in modulating brain function has rapidly increased over the past 10 years, albeit chiefly in animal models.
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The last decade has witnessed an exponentially growing interest in gut microbiota and the gut-brain axis in health and disease.
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The importance of the gut-brain axis in maintaining homeostasis has long been appreciated.
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The 'monoamine hypothesis' is insufficient in approaching the aetiology of psychiatric disorders or in developing novel therapies.
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The endotoxin hypothesis of neurodegeneration is the hypothesis that endotoxin causes or contributes to neurodegeneration.
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The kynurenine pathway is important in cellular energy generation and limiting cellular ageing as it degrades about 90% of dietary tryptophan into the essential co-factor NAD + (nicotinamide adenine dinucleotide).
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Psychobiotics are a group of probiotics that affect the central nervous system (CNS) related functions and behaviors mediated by the gut-brain-axis (GBA) via immune, humoral, neural, and metabolic pathways to improve not only the gastrointestinal (GI) function but also the antidepressant and anxiolytic capacity.
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The gut microbiota has emerged as an environmental factor that modulates the development of the central nervous system (CNS) and the enteric nervous system (ENS).
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The gut microbiota has been linked to various neurological disorders via the gut-brain axis.
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Gut dysbiosis, a primary factor behind various gastrointestinal disorders may also augment lipopolysaccharides, pro-inflammatory cytokines, T helper cells and monocytes causing increased intestinal and BBB permeability via microbiota-gut-brain axis.
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The gut-brain axis is increasingly recognized as an important pathway of communication and of physiological regulation, and gut microbiota seems to play a significant role in this mutual relationship.
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38/100
The number of bacterial cells living within the human body is approximately equal to, or greater than, the total number of human cells.
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55/100
In recent years evidence has emerged that neurodegenerative diseases (NDs) are strongly associated with the microbiome composition in the gut.
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Neurological diseases, such as Parkinson's disease, Alzheimer's disease, amyotrophic lateral sclerosis (ALS) and multiple sclerosis, are often associated with functional gastrointestinal disorders.
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39/100
Frailty, which is a syndrome that encompasses losses in physical, psychological and social domains, is responsible for enhanced vulnerability to endogenous and/or exogenous stressors.
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Parkinson's disease (PD) is a debilitating neurodegenerative condition associated with tremor, rigidity, dementia, and gastrointestinal symptoms such as constipation, nausea and vomiting.
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The human gut is a composite anaerobic environment with a large, diverse and dynamic enteric microbiota, represented by more than 100 trillion microorganisms, including at least 1000 distinct species.
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Though seemingly distinct and autonomous, emerging evidence suggests there is a bidirectional interaction between the intestinal microbiota and the brain.
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The purposes of this review were as follows: first, to provide an overview of the gut microbiota and its interactions with the gut and the central nervous system (the microbiota-gut-brain axis) in health, second, to review the relevance of this axis to the pathogenesis of neurodegenerative diseases, such as Parkinson's disease, and, finally, to assess the potential for microbiota-targeted therapies.
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-oxide (TMAO) is a small organic molecule, derived from the intestinal and hepatic metabolism of dietary choline and carnitine.
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38/100
There is a growing appreciation of the role of the gut microbiota in all aspects of health and disease, including brain health.
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The gut microbiota is essential to health and has recently become a target for live bacterial cell biotherapies for various chronic diseases including metabolic syndrome, diabetes, obesity and neurodegenerative disease.
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The gut and brain form the gut-brain axis through bidirectional nervous, endocrine, and immune communications.
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Almost half the cells and 1% of the unique genes found in our bodies are human, the rest are from microbes, predominantly bacteria, archaea, fungi, and viruses.
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Gut microbiota (GM) can influence various neurological outcomes, like cognition, learning, and memory.
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The diverse collection of microorganisms that inhabit the gastrointestinal tract, collectively called the gut microbiota, profoundly influences many aspects of host physiology, including nutrient metabolism, resistance to infection and immune system development.
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Gastro-intestinal (GI) microbiota and the 'gut-brain axis' are proving to be increasingly relevant to early brain development and the emergence of psychiatric disorders.
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The enteric nervous system (ENS) is large, complex and uniquely able to orchestrate gastrointestinal behaviour independently of the central nervous system (CNS).
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IBS is associated with an increased risk of dementia, and this effect is obvious only in patients who are ≥50 years old.
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The hypothesis of an important role of gut microbiota in the maintenance of physiological state into the gastrointestinal (GI) system is supported by several studies that have shown a qualitative and quantitative alteration of the intestinal flora in a number of gastrointestinal and extra-gastrointestinal diseases.
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The gut microbiome comprises the collective genome of the trillions of microorganisms residing in our gastrointestinal ecosystem.
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Epidemiological studies have shown a clear association between maternal infection and schizophrenia or autism in the progeny.
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Cytokine-induced sickness behavior was recognized within a few years of the cloning and expression of interferon-alpha, IL-1 and IL-2, which occurred around the time that the first issue of Brain, Behavior, and Immunity was published in 1987.
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In addition to a physiological role for CRF in integrating the responses of the brain, endocrine and immune systems to physiological, psychological and immunological stimuli, recent clinical data implicate CRF in the etiology and pathophysiology of various endocrine, psychiatric, neurologic and inflammatory illnesses.
From across this tag
6 of the 100 studies in this tag, picked by a fixed rule (a hash of each study's address), not by score or date; each page of this list shows a different 6. The same 6 appear here every time.
- Disorders of the enteric nervous system - a holistic view
- Enteric nervous system and intestinal epithelial regulation of the gut-brain axis
- Gut microbiota-derived metabolites and their importance in neurological disorders
- The relationship between gut microbiome and human diseases: mechanisms, predisposing factors and potential intervention
- Neurodegenerative Disorders and the Gut-Microbiome-Brain Axis: A Literature Review
- Probiotics, gut microbiota, and brain health: Exploring therapeutic pathways