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Home › Research › Topics › metabolism

metabolism

13 studies tagged metabolism, dated 1997-01-01 to 2025-02-01. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. SSRIs reduce plasma tau and restore dorsal raphe metabolism in Alzheimer's disease 2025-02-01
  2. Multi-omics data reveals aberrant gut microbiota-host glycerophospholipid metabolism in association with neuroinflammation in APP/PS1 mice 2023-11-22
  3. Effect of the ABCA1 agonist CS-6253 on amyloid-β and lipoprotein metabolism in cynomolgus monkeys 2022-06-24

Studies

13 studies carry this tag.

Date range

1997 to 2025

Top journals

  • Neurobiology of disease 2
  • Acta neuropathologica 1
  • Alzheimer's & dementia : the journal of the Alzheimer's Association 1
  • Alzheimer's research & therapy 1
  • Cell reports 1

12 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. SSRIs reduce plasma tau and restore dorsal raphe metabolism in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2025-02-01 Biomarkers

    Long-term SSRI use may reduce the pathological presentation of AD but has variable effects on cognitive performance.

  2. Multi-omics data reveals aberrant gut microbiota-host glycerophospholipid metabolism in association with neuroinflammation in APP/PS1 mice

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Gut microbes 2023-11-22 Genetics

    Numerous studies have described the notable impact of gut microbiota on the brain in Alzheimer's disease (AD) via the gut - brain axis.

  3. Effect of the ABCA1 agonist CS-6253 on amyloid-β and lipoprotein metabolism in cynomolgus monkeys

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Alzheimer's research & therapy 2022-06-24 Biomarkers

    Treatment with the ABCA1 agonist CS-6253 appears to favor Aβ clearance from the brain.

  4. ApoE4 Impairs Neuron-Astrocyte Coupling of Fatty Acid Metabolism

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Cell reports 2021-01-01 Genetics

    Alzheimer's disease (AD) risk gene ApoE4 perturbs brain lipid homeostasis and energy transduction.

  5. Microglia and lipids: how metabolism controls brain innate immunity

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Seminars in cell & developmental biology 2020-08-15 Genetics

    Microglia are universal sensors of alterations in CNS physiology.

  6. Striking while the iron is hot: Iron metabolism and ferroptosis in neurodegeneration

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Free radical biology & medicine 2018-09-25 Risk genes beyond APOE

    Perturbations in iron homeostasis and iron accumulation feature in several neurodegenerative disorders including Alzheimer's disease (AD), Parkinson's disease (PD) and Amyotrophic lateral sclerosis (ALS).

  7. Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Acta neuropathologica 2016-12-08 Genetics

    Genome-wide association studies (GWASs) have identified 19 susceptibility loci for Alzheimer's disease (AD).

  8. Evidence of altered phosphatidylcholine metabolism in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Neurobiology of aging 2013-09-13 Genetics

    Abberant lipid metabolism is implicated in Alzheimer's disease (AD) pathophysiology, but the connections between AD and lipid metabolic pathways are not fully understood.

  9. Homocysteine metabolism and cerebrospinal fluid markers for Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of Alzheimer's disease : JAD 2009-01-01 Biomarkers

    Disturbed homocysteine metabolism is a risk factor for Alzheimer's disease (AD) and may contribute to the disease pathophysiology by increasing both amyloid-beta (Abeta) production and phosphorylated tau (P-tau) accumulation.

  10. Regulation of cholesterol and sphingomyelin metabolism by amyloid-beta and presenilin

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Nature cell biology 2005-11-01 Risk genes beyond APOE

    Amyloid beta peptide (Abeta) has a key role in the pathological process of Alzheimer's disease (AD), but the physiological function of Abeta and of the amyloid precursor protein (APP) is unknown.

  11. In vivo assessment of brain interstitial fluid with microdialysis reveals plaque-associated changes in amyloid-beta metabolism and half-life

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The Journal of neuroscience : the official journal of the Society for Neuroscience 2003-10-01 Risk genes beyond APOE

    Soluble amyloid-beta (Abeta) peptide converts to structures with high beta-sheet content in Alzheimer's disease (AD).

  12. Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neurobiology of disease 2002-04-01 Genetics

    The epsilon4 allele of apolipoprotein E (apoE) is a risk factor for Alzheimer's disease (AD), perhaps through effects on amyloid-beta (Abeta) metabolism.

  13. Zinc metabolism in the brain: relevance to human neurodegenerative disorders

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neurobiology of disease 1997-01-01 Risk genes beyond APOE

    Pharmacological doses of zinc cause neuronal death, and some estimates indicate that extracellular concentrations of zinc could reach neurotoxic levels under pathological conditions.

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