Home › Research › Topics › markedly
markedly
3 studies tagged markedly, dated 2002-04-01 to 2016-12-01. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Vectored Intracerebral Immunization with the Anti-Tau Monoclonal Antibody PHF1 Markedly Reduces Tau Pathology in Mutant Tau Transgenic Mice 2016-12-01
- ApoE variant p.V236E is associated with markedly reduced risk of Alzheimer's disease 2014-03-10
- Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease 2002-04-01
Studies
3 studies carry this tag.
Date range
2002 to 2016
Top journals
- Molecular neurodegeneration 1
- Neurobiology of disease 1
- The Journal of neuroscience : the official journal of the Society for Neuroscience 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
-
Passive immunization with anti-tau monoclonal antibodies has been shown by several laboratories to reduce age-dependent tau pathology and neurodegeneration in mutant tau transgenic mice.
-
Recent genome-wide association studies (GWAS) of late-onset Alzheimer's disease (LOAD) have identified single nucleotide polymorphisms (SNPs) which show significant association at the well-known APOE locus and at nineteen additional loci.
-
The epsilon4 allele of apolipoprotein E (apoE) is a risk factor for Alzheimer's disease (AD), perhaps through effects on amyloid-beta (Abeta) metabolism.