longitudinal-cohort

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

1. 72/100

   Prediction of amyloid and tau brain deposition and cognitive decline in people with Down syndrome using plasma biomarkers: a longitudinal cohort study

   ✓ Peer-reviewed alzhub usefulness score 72 out of 100. The Lancet. Neurology · 2025-07-01 · Biomarkers

   Baseline p-tau217, as well as GFAP, NfL, or t-tau, were individually associated with longitudinal changes in DS-MSE, Aβ-PET, and tau-PET, and with progression to dementia.

   • Biomarkers
   • Down Syndrome
2. 69/100

   Timeline to symptomatic Alzheimer's disease in people with Down syndrome as assessed by amyloid-PET and tau-PET: a longitudinal cohort study

   ✓ Peer-reviewed alzhub usefulness score 69 out of 100. The Lancet. Neurology · 2024-12-01 · Brain scans and imaging

   Generalised linear regressions showed significant quadratic associations between amyloid age and cognitive performance and cubic associations between amyloid age and tau, both at baseline and at the 32-month follow-up.

   • Brain Scans
3. 72/100

   Subjective cognitive complaints and blood biomarkers of neurodegenerative diseases: a longitudinal cohort study

   ✓ Peer-reviewed alzhub usefulness score 72 out of 100. Alzheimer's research & therapy · 2023-11-11 · Biomarkers

   In community and clinical settings, SCC predict both dementia and depression in the absence of dementia.

   • Biomarkers
   • Early Stage
   • Genetics
4. 59/100

   Post-vaccination infection rates and modification of COVID-19 symptoms in vaccinated UK school-aged children and adolescents: A prospective longitudinal cohort study

   ✓ Peer-reviewed alzhub usefulness score 59 out of 100. The Lancet regional health. Europe · 2022-07-08 · Cognitive tests and assessment

   Between August 5, 2021 and February 14, 2022, 25,971 UK CA aged 12-17 years received one dose of BNT162b2 vaccine.

   • Prevention
5. 64/100

   Transition rates between amyloid and neurodegeneration biomarker states and to dementia: a population-based, longitudinal cohort study

   ✓ Peer-reviewed alzhub usefulness score 64 out of 100. The Lancet. Neurology · 2015-11-18 · Brain scans and imaging

   Our transition rates suggest that brain ageing is a nearly inevitable acceleration toward worse biomarker and clinical states.

   • Biomarkers

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