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longitudinal
9 studies tagged longitudinal, dated 2012-07-02 to 2024-01-01. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Longitudinal Phospho-tau217 Predicts Amyloid Positron Emission Tomography in Asymptomatic Alzheimer's Disease 2024-01-01
- Longitudinal cerebrospinal fluid measurements show glial hypo- and hyperactivation in predementia Alzheimer's disease 2023-12-13
- Alzheimer's disease diagnostic accuracy by fluid and neuroimaging ATN framework 2023-07-12
Studies
9 studies carry this tag.
Date range
2012 to 2024
Top journals
- Journal of neuroinflammation 2
- Alzheimer's research & therapy 1
- Brain : a journal of neurology 1
- Brain communications 1
- CNS neuroscience & therapeutics 1
8 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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An ECL immunoassay testing plasma P-tau217 accurately predicts amyloid PET positivity in cognitively unimpaired individuals.
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Cross-sectionally, CSF sTREM2, YKL-40, clusterin and fractalkine were higher only in groups with tau pathology, independent of amyloidosis (p < 0.001, A+/T+ or N+ and A-/T+ or N+, compared to A-/T-/N-).
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Our findings suggest that plasma, CSF, and neuroimaging biomarkers differ considerably within the ATN framework; the most accurate target biomarkers for diagnosing AD were the CSF-A, neuroimaging-T, and neuroimaging-N within each ATN modality.
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MMP-9 may have more detrimental effects on AD-related pathological and cognitive changes in women.
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67/100
Alzheimer's disease has a long asymptomatic phase that offers a substantial time window for intervention.
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Mixed-effect models assessed rates of memory decline in relation to baseline plasma p-tau181, and whether plasma p-tau181 significantly predicted memory decline beyond widely available clinical and genetic data (age, sex, years of education, cardiovascular and metabolic conditions, and APOE ε 4 status).
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Alzheimer's disease (AD) features a dynamic sequence of amyloid deposition, neurodegeneration, and cognitive impairment.
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Previous studies have demonstrated increased tau plasma levels in patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI) due to AD.
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These data suggest that amyloid dependent microgliosis may be Src kinase dependent in vitro and in vivo.