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long-term-treatment
3 studies tagged long-term-treatment, dated 2006-04-06 to 2011-01-01. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Long-term treatment with lithium alleviates memory deficits and reduces amyloid-β production in an aged Alzheimer's disease transgenic mouse model 2011-01-01
- Proteomic identification of brain proteins in the canine model of human aging following a long-term treatment with antioxidants and a program of behavioral enrichment: relevance to Alzheimer's disease 2006-10-20
- Reducing the risk of dementia: efficacy of long-term treatment of hypertension 2006-04-06
Studies
3 studies carry this tag.
Date range
2006 to 2011
Top journals
- Journal of Alzheimer's disease : JAD 1
- Neurobiology of aging 1
- Stroke 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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The glycogen synthase kinase-3β (GSK3β) pathway plays a central role in Alzheimer's disease (AD) and its deregulation accounts for many of the pathological hallmarks of AD.
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Aging canines develop cognitive dysfunction and neuropathology similar to those seen in humans, and the use of antioxidants results in reductions in oxidative damage and in improvement in cognitive function in this canine model of human aging.
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For each additional year of treatment there was a reduction in the risk of incident dementia (hazard ratio [HR]=0.94, 95% CI, 0.89 to 0.99).