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Newest in this topic

  1. Neuroprotective Impact of Linagliptin against Cadmium-Induced Cognitive Impairment and Neuropathological Aberrations: Targeting SIRT1/Nrf2 Axis, Apoptosis, and Autophagy 2023-07-27
  2. Neuroprotective Role of DPP-4 Inhibitor Linagliptin Against Neurodegeneration, Neuronal Insulin Resistance and Neuroinflammation Induced by Intracerebroventricular Streptozotocin in Rat Model of Alzheimer's Disease 2023-04-20
  3. Linagliptin, a DPP-4 inhibitor, ameliorates Aβ (1-42) peptides induced neurodegeneration and brain insulin resistance (BIR) via insulin receptor substrate-1 (IRS-1) in rat model of Alzheimer's disease 2021-06-11

Studies

6 studies carry this tag.

Date range

2019 to 2023

Top journals

  • International journal of molecular sciences 2
  • Frontiers in neurology 1
  • Neurochemical research 1
  • Neuropharmacology 1
  • Pharmaceuticals (Basel, Switzerland) 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Neuroprotective Impact of Linagliptin against Cadmium-Induced Cognitive Impairment and Neuropathological Aberrations: Targeting SIRT1/Nrf2 Axis, Apoptosis, and Autophagy

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Pharmaceuticals (Basel, Switzerland) 2023-07-27 Drug development

    Cadmium is an environmental contaminant associated with marked neurotoxicity and cognitive impairment.

  2. Alzheimer's disease (AD) is an age-related, multifactorial progressive neurodegenerative disorder manifested by cognitive impairment and neuronal death in the brain areas like hippocampus, yet the precise neuropathology of AD is still unclear.

  3. Alzheimer's disease (AD) is the most devastating neurodegenerative disorder, accounting over 46 million cases of dementia globally.

  4. Neuroprotective Properties of Linagliptin: Focus on Biochemical Mechanisms in Cerebral Ischemia, Vascular Dysfunction and Certain Neurodegenerative Diseases

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. International journal of molecular sciences 2019-08-20 Drug development

    Linagliptin is a representative of dipeptidyl peptidase 4 (DPP-4) inhibitors which are registered and used effectively in a treatment of diabetes mellitus type 2.

  5. The Dipeptidyl Peptidase-4 Inhibitor Linagliptin Ameliorates High-fat Induced Cognitive Decline in Tauopathy Model Mice

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. International journal of molecular sciences 2019-05-23 Drug development

    Vascular risk factors, such as type 2 diabetes mellitus (T2DM), are associated with the increased risk of Alzheimer's disease.

  6. Dipeptidyl Peptidase-4 Inhibitors for the Potential Treatment of Brain Disorders; A Mini-Review With Special Focus on Linagliptin and Stroke

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Frontiers in neurology 2019-05-08 Drug development

    Cerebral stroke is a leading cause of death and persistent disability of elderly in the world.

All topic tags with their study counts