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lifespan
2 studies tagged lifespan, dated 2009-12-04 to 2023-01-01. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Tryptophan Metabolism and Neurodegeneration: Longitudinal Associations of Kynurenine Pathway Metabolites with Cognitive Performance and Plasma Alzheimer's Disease and Related Dementias Biomarkers in the Duke Physical Performance Across the LifeSpan Study 2023-01-01
- Evolution in health and medicine Sackler colloquium: Evolution of the human lifespan and diseases of aging: roles of infection, inflammation, and nutrition 2009-12-04
Studies
2 studies carry this tag.
Date range
2009 to 2023
Top journals
- Journal of Alzheimer's disease : JAD 1
- Proceedings of the National Academy of Sciences of the United States of America 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Our findings provide evidence that greater concentrations of KP metabolites are associated longitudinally over two years with greater biomarker evidence of neurofibrillary tau pathology (pTau-181), neuroinflammation (GFAP), and neurodegeneration (NfL), suggesting that dysregulated KP metabolism may play a role in ADRD pathogenesis.
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Humans have evolved much longer lifespans than the great apes, which rarely exceed 50 years.