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Newest in this topic

  1. Rat nicastrin gene: cDNA isolation, mRNA variants and expression pattern analysis 2005-03-16
  2. Activity-dependent isolation of the presenilin- gamma -secretase complex reveals nicastrin and a gamma substrate 2002-02-26

Studies

2 studies carry this tag.

Date range

2002 to 2005

Top journals

  • Brain research. Molecular brain research 1
  • Proceedings of the National Academy of Sciences of the United States of America 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Rat nicastrin gene: cDNA isolation, mRNA variants and expression pattern analysis

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Brain research. Molecular brain research 2005-03-16 Drug development

    Nicastrin is a type 1 transmembrane glycoprotein that interacts with presenilin, Aph-1, and Pen-2 proteins to form a high molecular complex with gamma secretase activity.

  2. Activity-dependent isolation of the presenilin- gamma -secretase complex reveals nicastrin and a gamma substrate

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2002-02-26 Risk genes beyond APOE

    Presenilin heterodimers apparently contain the active site of gamma-secretase, a polytopic aspartyl protease involved in the transmembrane processing of both the Notch receptor and the amyloid-beta precursor protein.

All topic tags with their study counts