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ippi
3 studies tagged ippi, dated 2020-08-06 to 2025-07-01. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- [125I]IPPI for Tau Imaging: Binding Studies in Postmortem Human Alzheimer's Disease Hippocampus-Subiculum and Evaluation of Drug Effects 2025-07-01
- Measurement of Aβ Amyloid Plaques and Tau Protein in Postmortem Human Alzheimer's Disease Brain by Autoradiography Using [18F]Flotaza, [125I]IBETA, [124/125I]IPPI and Immunohistochemistry Analysis Using QuPath 2023-03-27
- Development and evaluation of [125 I]IPPI for Tau imaging in postmortem human Alzheimer's disease brain 2020-08-06
Studies
3 studies carry this tag.
Date range
2020 to 2025
Top journals
- Synapse (New York, N.Y.) 2
- Biomedicines 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Alzheimer's disease (AD) is characterized by the accumulation of tau tangles that aggregate into neurofibrillary tangles (NFT).
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High-resolution scans of immunohistochemical (IHC) stains of Alzheimer's disease (AD) brain slices and radioligand autoradiography both provide information about the distribution of Aβ plaques and Tau, the two common proteinopathies in AD.
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[ 125 I]IPPI exhibited high binding in human AD frontal cortex and anterior cingulate and is a suitable radioiodinated ligand for Tau imaging.