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intrinsic
3 studies tagged intrinsic, dated 2010-11-12 to 2020-08-24. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- γ-Secretase cleavage of the Alzheimer risk factor TREM2 is determined by its intrinsic structural dynamics 2020-08-24
- Within-patient correspondence of amyloid-β and intrinsic network connectivity in Alzheimer's disease 2014-04-26
- Spatial patterns of intrinsic brain activity in mild cognitive impairment and Alzheimer's disease: a resting-state functional MRI study 2010-11-12
Studies
3 studies carry this tag.
Date range
2010 to 2020
Top journals
- Brain : a journal of neurology 1
- Human brain mapping 1
- The EMBO journal 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Sequence variants of the microglial expressed TREM2 (triggering receptor expressed on myeloid cells 2) are a major risk factor for late onset Alzheimer's disease.
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However, the observed spatial extent of amyloid-β exceeds these tightly circumscribed areas, suggesting that previous studies may have underestimated the negative impact of amyloid-β on intrinsic connectivity.
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We used resting-state functional MRI to investigate spatial patterns of spontaneous brain activity in 22 healthy elderly subjects, as well as 16 mild cognitive impairment (MCI) and 16 Alzheimer's disease (AD) patients.