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improved
4 studies tagged improved, dated 2014-12-04 to 2022-03-12. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Identification of the Aβ37/42 peptide ratio in CSF as an improved Aβ biomarker for Alzheimer's disease 2022-03-12
- Identification and in vitro characterization of C05-01, a PBB3 derivative with improved affinity for alpha-synuclein 2020-09-18
- Improved power for characterizing longitudinal amyloid-β PET changes and evaluating amyloid-modifying treatments with a cerebral white matter reference region 2015-03-05
Studies
4 studies carry this tag.
Date range
2014 to 2022
Top journals
- Alzheimer's & dementia : the journal of the Alzheimer's Association 1
- Brain research 1
- Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1
- NeuroImage 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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We conclude that the Aβ 37/42 ratio sensitively detects presenilin/γ-secretase dysfunction and better distinguishes CN from AD than Aβ42/40 in CSF.
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The neuropathological hallmark of Parkinsońs disease, multiple system atrophy and dementia with Lewy bodies is the accumulation of α-synuclein.
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A cerebral white matter reference region may improve the power to track longitudinal fibrillar Aβ increases, to characterize their relationship to longitudinal clinical declines, and to evaluate Aβ-modifying treatments in randomized clinical trials.
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Amyloid positron-emission-tomography (PET) offers an important research and diagnostic tool for investigating Alzheimer's disease (AD).