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immunization
5 studies tagged immunization, dated 2012-02-01 to 2016-12-01. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Vectored Intracerebral Immunization with the Anti-Tau Monoclonal Antibody PHF1 Markedly Reduces Tau Pathology in Mutant Tau Transgenic Mice 2016-12-01
- Tau immunization: a cautionary tale? 2014-12-30
- Anti-amyloid beta to tau - based immunization: Developments in immunotherapy for Alzheimer disease 2013-08-01
Studies
5 studies carry this tag.
Date range
2012 to 2016
Top journals
- Experimental neurology 1
- ImmunoTargets and therapy 1
- Immunotherapy 1
- Neurobiology of aging 1
- The Journal of neuroscience : the official journal of the Society for Neuroscience 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Passive immunization with anti-tau monoclonal antibodies has been shown by several laboratories to reduce age-dependent tau pathology and neurodegeneration in mutant tau transgenic mice.
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The amyloid β (Aβ)-protein and microtubule-associated protein, tau, are the major components of the amyloid plaques and neurofibrillary tangles that typify Alzheimer's disease (AD) pathology.
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40/100
Immunotherapy might provide an effective treatment for Alzheimer disease (AD).
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The recent studies of others and of us showing robust efficacy of anti-tangle immunotherapy, directed against phosphorylated (phos)-tau protein, may pave the way to clinical trials of phos-tau immunotherapy in Alzheimer's-disease and other tauopathies.
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36/100
The exact mechanisms leading to Alzheimer's disease (AD) are largely unknown, limiting the identification of effective disease-modifying therapies.