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Newest in this topic

  1. The dual role of microglia in Alzheimer's disease: from immune regulation to pathological progression 2025-03-27
  2. Friend, Foe or Both? Immune Activity in Alzheimer's Disease 2019-12-10
  3. Chromatin activity at GWAS loci identifies T cell states driving complex immune diseases 2019-09-23

Studies

6 studies carry this tag.

Date range

2016 to 2025

Top journals

  • Frontiers in aging neuroscience 2
  • Acta neuropathologica 1
  • Molecular neurodegeneration 1
  • Nature genetics 1
  • Neurology. Genetics 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. The dual role of microglia in Alzheimer's disease: from immune regulation to pathological progression

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Frontiers in aging neuroscience 2025-03-27 TREM2 and immune genetics

    Alzheimer's disease (AD) is a widespread neurodegenerative disorder and one of the major challenges for public health.

  2. Friend, Foe or Both? Immune Activity in Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Frontiers in aging neuroscience 2019-12-10 Genetics

    Alzheimer's disease (AD) is marked by the presence of amyloid beta (Aβ) plaques, neurofibrillary tangles (NFT), neuronal death and synaptic loss, and inflammation in the brain.

  3. Chromatin activity at GWAS loci identifies T cell states driving complex immune diseases

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Nature genetics 2019-09-23 Genetics

    Immune-disease-associated variants are enriched in active chromatin regions of T cells and macrophages.

  4. Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimer's disease-related proteins

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Molecular neurodegeneration 2018-06-28 Genetics

    Our results were also contrasted with existing proteomic data from wild-type mouse microglia and from existing microglial transcriptomic data from wild-type and 5xFAD mice.

  5. Vascular, glial, and lymphatic immune gateways of the central nervous system

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Acta neuropathologica 2016-08-13 Tau biomarkers

    Immune privilege of the central nervous system (CNS) has been ascribed to the presence of a blood-brain barrier and the lack of lymphatic vessels within the CNS parenchyma.

  6. Trans-pQTL study identifies immune crosstalk between Parkinson and Alzheimer loci

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. Neurology. Genetics 2016-07-26 TREM2 and immune genetics

    We find that the rs12456492 PD risk variant affects expression of AD-associated protein CD33 in peripheral monocytes, which suggests that genetic factors for these 2 diseases may converge to influence overlapping innate immune-mediated mechanisms that contribute to neurodegeneration.

All topic tags with their study counts