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identification
9 studies tagged identification, dated 2002-01-01 to 2025-12-22. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Pharmacologic reversal of advanced Alzheimer's disease in mice and identification of potential therapeutic nodes in human brain 2025-12-22
- Identification of circulating risk biomarkers for cognitive decline in a large community-based population in Chongqing China 2024-12-23
- Identification of the Aβ37/42 peptide ratio in CSF as an improved Aβ biomarker for Alzheimer's disease 2022-03-12
Studies
9 studies carry this tag.
Date range
2002 to 2025
Top journals
- Alzheimer's & dementia : the journal of the Alzheimer's Association 2
- Frontiers in aging neuroscience 2
- BMC biology 1
- Cell reports. Medicine 1
- Frontiers in cellular neuroscience 1
7 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Alzheimer's disease (AD) is traditionally considered irreversible.
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The common and distinct risk factors across cognitive decline stages emphasize the need for tailored interventions.
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We conclude that the Aβ 37/42 ratio sensitively detects presenilin/γ-secretase dysfunction and better distinguishes CN from AD than Aβ42/40 in CSF.
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The recent development of ultrasensitive technology allows the determination of blood-based biomarkers with high sensitivity, thus facilitating the early detection of AD through the analysis of easily obtained biological samples.
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After adjusting for age, sex, and the apolipoprotein E ( APOE ) alleles, compared to the CN group, the plasma t-tau, and NfL were significantly increased in the AD group ( p < 0.01, Bonferroni correction).
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The rate of cognitive decline among patients with amnestic mild cognitive impairment (aMCI) varies, and it is thus crucial to accurately predict the probability of cognitive deterioration in patients with MCI.
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Our findings identify Syt1 as a novel Ca(2+)-sensitive PS1 modulator that could regulate synaptic Aβ, opening avenues for novel and selective synapse targeting therapeutic strategies.
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Alzheimer's disease (AD) is a neurodegenerative disorder characterized clinically by the progressive decline of memory and cognition.
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Chronic neuroinflammatory processes including glial activation may play a role in the pathogenesis of Alzheimer's disease (AD).