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hydromethylthionine
3 studies tagged hydromethylthionine, dated 2019-01-01 to 2022-01-01. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Oral Tau Aggregation Inhibitor for Alzheimer's Disease: Design, Progress and Basis for Selection of the 16 mg/day Dose in a Phase 3, Randomized, Placebo-Controlled Trial of Hydromethylthionine Mesylate 2022-01-01
- Proteomic Analysis of Hydromethylthionine in the Line 66 Model of Frontotemporal Dementia Demonstrates Actions on Tau-Dependent and Tau-Independent Networks 2021-08-22
- Concentration-Dependent Activity of Hydromethylthionine on Cognitive Decline and Brain Atrophy in Mild to Moderate Alzheimer's Disease 2019-01-01
Studies
3 studies carry this tag.
Date range
2019 to 2022
Top journals
- Cells 1
- Journal of Alzheimer's disease : JAD 1
- The journal of prevention of Alzheimer's disease 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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If the primary end points are met, the data will provide confirmatory evidence of the clinical and biomarker benefits of hydromethylthionine mesylate in minimal to moderate AD.
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Abnormal aggregation of tau is the pathological hallmark of tauopathies including frontotemporal dementia (FTD).
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Hydromethylthionine has pharmacological activity on brain structure and function at the 8 mg/day dose as monotherapy or as add-on to symptomatic treatments.